Typographers had big debates when Apple launched the first iPads and iPhones with retina displays ("Retina" is the marketing name for a screen with such a high pixel density that your eyes cannot see individual pixels anymore). Retina displays are obviously different from low resolution screens, but - as the typographers discovered - are also different from paper/print.
I now see similar issues with large retina monitors. A traditional PowerPoint presentation with an Arial or Calibri font looks somehow off. You need lighter, thinner, crisper fonts. Macs have Helvetica light installed, but Windows machines not. Drop shadows look "dirty". Outlines around boxes look too heavy.
My guess is that Microsoft will fix the font issue in upcoming releases of Windows and Office products. But, if we fix the issue for computer screens, we are still left with this huge install base of crappy VGA overhead projectors in corporate conference rooms that never get replaced...
If you are working on a really important, one off, presentation find out about the screen you are going to present on and test your design.
Art: Vincent van Gogh, Starry night, drawing, 1889