On Quora, I see questions like which presentation software did [company X] use at [event Y]. For the audience there is no difference. The same simple, good slide can be made in PowerPoint, Keynote, Google Slides, and Adobe InDesign. The exception is probably Prezi and its complex zooming capabilities.
The process that got you there makes a big difference though. How easy is it set up a basic presentation template (colours, fonts, positions of titles, page numbers, aspect ratio), how is it to create a basic slide layout other than a list of bullets, how easy is it to align items properly on a grid, how easy is to create basic data charts, how easy is it to keep everything consistent page after page, how easy is it to do basic image manipulation (cropping and repositioning).
Either the audience cannot tell in which program the presentation was made and you were either a design pro or have made a huge effort to master the software. Or, the audience can spot your software instantly (most likely PowerPoint), which means that you did not get much further than the standard slide template.
(A secret: you can get away with taking design short cuts in my presentation app SlideMagic and no one will notice).
Edgar Degas, Rehearsal on stage, 1874