My old Apple Thunderbolt screen has had its best time, so I find myself back with just on 5K screen on my iMac recently. And I must say: I might keep this desk configuration. It creates a nicer work environment where I can actually look out of the window (over the Mediterranean in my case), with less clutter and big bright light beams shining in your face.
There is now no longer space to keep Twitter feeds and other distractions open on your screen. Also side-by-side design work where I have a spreadsheet and a presentation open at the same time somehow works actually better: moving your eye from document to the next, and looking for that number is quicker when everything is right in front of you.
We will see what happens after a few weeks.