If you have to say for the 3rd time in a presentation "be patient, we will get to that in slide 42", it might be time to switch to the topic of page 42, even if you only got to slide 5.

Your persistence gave you points as CEO for not giving up easily, but you also lost some because of lack of flexibility as a person to work with and give feedback to. Or worse, the investor think that you will continue to drive down the planned road even if circumstances have changed and require a change of plan. 

Afterwards, think again about the order of your slides, maybe slide 42 needs to come up earlier. Maybe it addresses an "elephant in the room", big question. For example it is unusual to put the competition analysis on slide 1 of your presentation, but for example, If you are planning to build a website where people can search the internet, you might have to.

Obviously, going of script works only in small settings, switching the flow of a major keynote address in front of 100s of people is a bit harder to do.

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